Biochemical Pathways Database under C@ROL

The Database

BioPath is a database of biochemical pathways that provides access to metabolic transformations and cellular regulations derived from the Roche Applied Science "Biochemical Pathways" wall chart.

BioPath contains a library of cross-linked biochemical molecules and reactions. All structure and reaction information is stored on an atomic level allowing the direct access to all atoms and bonds of all metabolites and to the bonds broken and made during an enzymatic reaction.

BioPath is designed to support scientists to understand the impact of gene regulations on biological systems for drug target identification and provides the following features:

  • 1,175 molecules with connection tables including stereochemical information
  • 1,545 biochemical reactions stoichiometrically balanced, with marked reaction centers and atom-atom mapping numbers between educts and products
  • 1,000 unique enzymes represented by names and EC numbers
  • 202 pathways represented by names
  • Covered organism: prokaryotes, plants, yeasts and animals, general pathways
  • Subcellular localization of pathways (cytosol, chloroplasts, mitochondria, ...)

The Software

C@ROL is a chemical warehouse system designed to store 2D structures, multiple 3D conformations and chemical reactions along with textuell data. The web-based user interface provides access to the features of the structure search engine for the retrieval of chemical compounds and their related data. This engine can perform structure and sub-structure searches, similarity searches, transformation searches, and reaction searches.

Try it!

You also can change between both search modes later any time.